SPNS & Demonstration Project Directory

HRSA supports innovation though programs like Special Projects of National Significance (SPNS) and similar projects. These projects test models over multiple years, evaluating the design, implementation, utilization, cost, and health-related outcomes of treatment models. Models that work are then promoted for dissemination and replication by other agencies. 

This page lists resources available on TargetHIV that were derived from HRSA's SPNS program. Some resources were informed by multiple SPNS initiatives so are listed multiple times.

Active Demonstration and Evaluation Projects

Resources Developed by Initiatives

See the Advanced Search in the resource library for a complete collection of replication resources and job tools, filterable by topic, source, type, and date.

2iS - Implementation Science & Innovative Interventions

Accelerating Implementation of Long-Acting Injectables

American Indian/Alaska Native Initiative

Assessing Evidence-Informed Approaches for Improving Outcomes

Behavioral Health Interventions among Black MSM

Black Women First Initiative

Buprenorphine Opioid Addiction Treatment

Capacity Building in the Ryan White HIV/AIDS Program to Support Innovative Program Model Replication

Community Health Workers for Retention in HIV Care

Corrections Demonstration Project (CDP)

Curing HCV in HIV Coinfected POC - Jurisdictions

Dissemination of Evidence-Informed Interventions (DEII)

Electronic Networks of Care Initiative

Emerging Strategies to Improve Health Outcomes for People Aging with HIV

Employment and Housing Service Coordination

Engaging Young MSM of Color

EnhanceLink - Access to Care from Jail Settings

HCV Cure: PLWH of Color and SUD

HCV Treatment Expansion Initiative

HIV Positive Substance Users

HIV-STI Data Linkages

HIV/HCV Data to Care

Housing Data Integration

Latino Access Initiative

Med-HEART - Medical Homes for Multiply-Diagnosed

Opioid Treatment Approaches

Oral Health

Outreach Model Development for Underserved PLWH

Peer Support in Caribbean-Americans Living with HIV

Rapid ART Dissemination Assistance Provider

Rapid Start

SNAP: Status Neutral, Whole-Person Approaches to Services

Social Media for Engagement and Retention

STI Screening and Treatment

SURE Housing Interventions

Systems Linkages

Telehealth Strategies to Maximize HIV Care

Testing Evidence-Informed Approaches for Improving Outcomes (E2i)

Transgender Women of Color Engagement and Retention

U.S.-Mexico Border Service Innovation

Viral Suppression Data: Medicaid Data Set

Women of Color Initiative

Workforce Capacity Building in Community Settings