Updated hepatitis C screening recommendations call for at least one-time hepatitis C screening for all adults over 18 years of age and for pregnant women, for every pregnancy. CDC Recommendations for Hepatitis C Screening Among Adults — United States, 2020 reads, in part:
"CDC is augmenting previous guidance with two new recommendations: 1) hepatitis C screening at least once in a lifetime for all adults aged ≥18 years, except in settings where the prevalence of HCV infection is <0.1% and 2) hepatitis C screening for all pregnant women during each pregnancy, except in settings where the prevalence of HCV infection is <0.1%. The recommendation for HCV testing that remains unchanged is regardless of age or setting prevalence, all persons with risk factors should be tested for hepatitis C, with periodic testing while risk factors persist. Any person who requests hepatitis C testing should receive it, regardless of disclosure of risk, because many persons might be reluctant to disclose stigmatizing risks."
The recommendation, presented in the April 10, 2020 MMWR, states that "[a]n estimated 44,700 new cases of HCV infection occurred in 2017. The rate of reported acute HCV infections increased from 0.7 cases per 100,000 population in 2013 to 1.0 in 2017" (see below Figure 1). Figure 2 presents hepatitis C prevalence, by state, for adults and pregnant women.