A March 13, 2025 MMWR report analyzing neurosyphilis, ocular syphilis, and otic syphilis (NOO syphilis) cases in Chicago in 2023 found an increase in cases among HIV-negative heterosexual individuals, a contrast to 2019 data when most NOO syphilis cases were among men who have sex with men and persons with HIV. There were 2,611 cases of syphilis in Chicago in a nine-month reporting period in 2023, of which 40 were NOO syphilis cases.
Read more in Notes from the Field: Neurosyphilis, Ocular Syphilis, and Otic Syphilis — Chicago, January–October 2023.