Criteria for Interventions in the Best Practices Compilation

The goal of the Ryan White HIV/AIDS Program (RWHAP) Recipient Compilation of Best Practice Intervention Strategies (Best Practices Compilation) is to gather and share what works in the RWHAP. The Best Practices Compilation includes intervention strategies that have been implemented in real world settings and improve outcomes along the HIV care continuum.

How are emerging interventions defined?

For intervention strategies to be included as an emerging intervention,* they need to meet the following criteria.

  1. Implemented in a RWHAP-funded setting.
  2. Implemented for at least 12 months, or if less than 12 months in response to a public health emergency (for example the COVID-19 pandemic).
  3. Demonstrated positive change influencing one or more HIV care continuum outcomes.
  4. Outcome evaluation results are not yet published in a peer-reviewed journal or currently under review by a peer-reviewed journal for publication. 
    • Note this does not include publication of descriptive information or process evaluation results.
  5. Your organization is willing to share the strategy with the RWHAP community on

How are emerging interventions different from evidence-based and evidence-informed interventions?

The Health Resources and Services Administration, HIV/AIDS Bureau, in collaboration with Centers for Disease Control and Prevention and National Institutes of Mental Health, developed three categories of intervention strategies for the RWHAP: emerging interventions, evidence-informed interventions, and evidence-based interventions.1 See summary guidelines below.

Summary of Guidelines to Assess Different Levels of Evidence

All intervention levels must have demonstrated effectiveness in improving the care and treatment of people with HIV. In addition, each level must also meet the following criteria:




Innovative strategies that address emerging priorities for improving the care and treatment of people with HIV. Real world validity and effectiveness have been demonstrated but emerging interventions do not yet have sufficient published research evidence.

Published research evidence meets HRSA evidence-informed criteria but does not meet CDC criteria for evidence-based interventions. It may also meet CDC criteria for evidence informed interventions.

Published research evidence supporting these interventions meets Centers for Disease Control and Prevention (CDC) criteria for being evidence-based.

Please contact us with any questions.

* Note: Emerging interventions were formerly known as emerging strategies.

1. Psihopaidas D, Cohen SM, West T, et al. (2020) Implementation science and the Health Resources and Services Administration’s Ryan White HIV AIDS Program’s work towards ending the HIV epidemic in the United States. PLoS Med 17(11):e1003128.