Dr. Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases and Chief Medical Advisor to the President, presented a summary of the HIV landscape, domestic and global, covering data on progress made in both treatment and care, research on what more potential can be expected, and the lagging challenges we face. Dr. Fauci also presented a rapid-fire review of research studies on treatment, prevention, and vaccine studies and focused them around two major components—closing implementation gaps and developing new and improved interventions. He closed with the observation that ending the HIV epidemic requires us to follow the science but take these scientific advances and implement them with a strong concentration on equity in their application.