Innovative Intervention Strategies (2iS)

This is a HRSA Special Programs of National Significance (SPNS) project titled Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV (2iS). It includes funding for a Technical Assistance Center (Fenway), an Evaluation Center (UCSF), and up to twenty demonstration sites (TBD).


  • To apply the HRSA HAB implementation science framework to identify innovative intervention strategies.
  • Pilot test the intervention strategies at up to 20 Ryan White HIV/AIDS Program-funded recipient organizations.
  • Provide technical assistance to support implementation at the sites.
  • Develop accessible dissemination products to promote the replication and scale-up of successful intervention strategies in the RWHAP and other HIV service organizations nationally. 

Focus Areas

The project's focus includes three priority populations and one area of service delivery:

  • People with Substance Use Disorder (SUD)
  • Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ+) youth
  • People who are or have been justice involved
  • Using Telehealth Services

Contact Information

Project Contacts:

Alex Keuroghlian, MD, MPH
Project Director, Implementation & Technical Assistance Center
Fenway Health
Janet Myers, PhD, MPH
Director, Evaluation Center
University of California, San Francisco

HRSA Contacts:

PO Name
Nicole Chavis
PO Title
Project Officer, Implementation & Technical Assistance Center
PO Name
Melanie Moore
PO Title
Project Officer, Evaluation Center
PO Name
Demetrios Psihopaidas, PhD, MA
PO Title
HRSA HAB Division of Policy and Data


Funding Mechanism: Cooperative Agreement

Recipient Organization: The Fenway Institute, UCSF

Grant number: HRSA-21-076, HRSA-21-068

Project Period: May 2021– April 2025