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Doxycycline that is taken as post-exposure prophylaxis (PEP) is effective in reducing the incidence of chlamydia and gonorrhea in men who have sex with men and transgender women.News Article updated on 04/11/2023
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Advancing Implementation Science: HRSA Technical Expert Panel Insights
Overview of implementation science activities for the Ryan White HIV/AIDS Program (RWHAP) and feedback on future directions.News Article updated on 04/14/2023 -
Eradicating Racism and Striving for Excellence in HIV Care (ERASE)
ERASE was developed to address the unique needs of Black MSM. Through an intensive case management intervention, peer case managers provide health education and wellness support, and connect clients to medical and behavioral healthcare. ERASE also offers a physical “safe space” for Black MSM to meet with a case manager, access medical services, or connect with peers. Enrollment in ERASE improved retention in HIV care for clients.Resource from the RWHAP Best Practices Compilation updated on 01/09/2024
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Health Centers on the Front Lines Podcast: Status Neutral
Review of concept of status neutral (access to HIV services regardless of HIV status).Resource updated 10/24/2023
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Health Centers on the Front Lines Podcast: Get to know! Long-Acting injectable PrEP and HIV treatment
In 2021, the U.S. public was introduced to a bi-monthly injectable form of PrEP, which stands for Pre-Exposure Prophylaxis.Resource updated 05/11/2023
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Micro Learning: Get to know! Long-Acting Injectable PrEP and HIV Treatment
Review of types of injectable long lasting HIV prevention and treatment medications and their similarities and differences.Resource updated 12/19/2023
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Health Centers on the Front Lines: Be the Change: Black Cisgender and Trans Women, HIV Treatment, & PrEP
Role of health centers in increasing PrEP access and use among women.Resource updated 10/18/2023
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Micro Learning: Black Cisgender and Trans Women, HIV Treatment, & PrEP
Learn how to improve messaging about HIV prevention and care to improve acceptance of services among all Black women.Resource updated 05/10/2023
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Project Strength Through Youth Livin' Empowered (STYLE) 2.0
STYLE 2.0 is a multi-component intervention designed to help reduce stigma and social isolation for Black gay, bisexual, and other men who have sex with men. The intervention relies on health care navigators who facilitate linkage and engagement activities. They also connect clients to behavioral health providers who conduct motivational interviewing, as well as to a mobile application that supports all intervention activities. STYLE 2.0 participation has been associated with positive trends across HIV care continuum outcomes, including retention in care and increased viral suppression.Resource from the RWHAP Best Practices Compilation updated on 11/30/2023
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weCare Social Media Intervention
In weCare, a cyber health educator sent personalized messages through text, web-based apps, and Facebook to enrolled youth who identified as gay, bisexual, or other men who have sex with men (MSM), or transgender women, and who either had a new diagnosis of HIV or were not in care at the time of enrollment. Messages were personalized to each participant’s needs and were designed to support them as they navigated complicated health care systems as well as other challenges that affect care engagement (e.g., transportation, disclosure). The cyber health educator also moderated and posted information about health and well-being on an optional secret Facebook page that some participants chose to join. Participants were less likely to miss medical appointments and more likely to be virally suppressed after 12 months of the intervention.Resource from the RWHAP Best Practices Compilation updated on 01/07/2024
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Medical Home for Multiply Diagnosed HIV-Positive Homeless Populations
The RWHAP Part F SPNS program funded the Building a Medical Home for Multiply Diagnosed HIV-Positive Homeless Populations initiative from 2012–2017, to provide coordinated housing supports and HIV, behavioral and mental health care to people experiencing homelessness. Nine funded demonstration sites created partnerships with housing providers, integrated behavioral health and HIV care, and provided intensive patient navigator services. A multi-demonstration site evaluation found that, compared to baseline, participants were more likely to be virally suppressed after 12 months in the intervention.Resource from the RWHAP Best Practices Compilation updated on 11/13/2023
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SPNS Initiative: Accelerating Implementation of Long-Acting Injectables (2022-2026)
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Positively Connected for Health (PC4H)
The PC4H initiative employs a mobile app and a digital literacy workshop to improve engagement, retention in care, and medication adherence for young people with HIV. These strategies aim to reach young people who are disproportionately affected by HIV, including young men who have sex with men, young transgender women, and youth of color, with a focus on serving people who know their status but are inconsistently engaged in care. Developed by Children’s Hospital of Philadelphia and Philadelphia FIGHT, PC4H was evaluated through the RWHAP Part F SPNS Social Media Initiative. The evaluation found that PC4H had positive impacts on retention in care and viral suppression.Resource from the RWHAP Best Practices Compilation updated on 11/17/2023
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HIV Clinical Pharmacist Services
The HIV Clinical Pharmacist Services intervention shortens the time between referral to and engagement in care by allowing newly referred clients to see pharmacists in addition to other clinical providers for their initial appointment. This intervention is supported by findings from a retrospective cohort study that took place from 2013 to 2017 at a RWHAP-funded clinic. In addition to significantly decreasing the time between referral and initial visit, clients who saw a pharmacist also experienced shortened time to antiretroviral therapy initiation and viral suppression compared to those who only saw non-pharmacist providers.Resource from the RWHAP Best Practices Compilation updated on 11/01/2023
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Behavioral Health Models to Improve HIV Health Outcomes for Black Men Who Have Sex With Men
Resources to facilitate the replication or adaption of successful interventions for engaging Black MSM in HIV care.Resource updated 03/04/2024
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Trends, Patterns, and Factors Associated with HIV Coinfection Among Male Syphilis Cases, 2014-2019, Hawaii
By cross matching registries of HIV and other sexually transmitted infections, this study found 27.1% of male syphilis cases were coinfected with HIV and 31.8% of those coinfected were not virally suppressed. This suggests ongoing sexual risk behaviors and the potential for HIV transmission among male syphilis cases.
Resource (Conference Presentation) updated 09/14/2023
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Simplifying Salvage Antiretroviral Regimens in Treatment-Experienced PLWH
In a single-center restrospective cohort study, patients with extensive treatment experience and history of virologic failure and multi-drug resistance underwent simplification of ARV salvage regimens with a median pill burden reduction of six pills per day. This strategy led to high rates of virologic suppression.
Resource (Conference Presentation) updated 09/14/2023
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HIV Clinic Staff and Community Perspectives on Long-Acting Injectable ART in New York City
The first long-acting injectable antiretroviral therapy (LAI ART) formulation was FDA-approved January 2021. Drawing on the Consolidated Framework on Implementation Research, this mixed methods study assessed knowledge, attitudes, practices, and perceived barriers and facilitators related to implementation of LAI ART in NYC among HIV clinic staff and people with HIV.
Resource (Conference Presentation) updated 09/14/2023
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Assessing Medication Access Barriers in Patients Living with HIV
Virginia quality improvement program that identifies access to medication barriers and provides emergency medication supplies to people with HIV if no timely access is secured.
Resource (Conference Presentation) updated 09/14/2023
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Long-Acting HIV Treatment Demonstrates Efficacy in People with Challenges Taking Daily Medicine as Prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen.News Article updated on 02/28/2024