Liver disease that is tied to Hepatitis C (HCV) infection is a leading cause of death among HIV-infected individuals. Hepatitis B is also a major challenge for many people with HIV. Ryan White-funded clinics are taking on a greater role in not only managing HCV disease but also providing HCV treatments. 

Resources 23

Best Practices

  • University of Texas Health, San Antonio, SPNS HCV Cure among People of Color with HIV
    Slides with summaries of the SPNS initiative, Curing Hepatitis C among People of Color Living with HIV including: evaluation questions; dissemination activities; and site reports.
  • IHIP

    These resources synthesize findings from the federally funded SPNS Hepatitis C Treatment Expansion Initiative, which focused on HCV treatment among coinfected patients.

  • Best Practices Compilation
    The Michigan Department of Health and Human Services was one of seven health departments funded by Leveraging a Data to Care Approach to Cure Hepatitis C Virus (HCV) Within the RWHAP Part F SPNS initiative implemented from 2020–2022. With the support of the Yale University School of Medicine, which served as the Technical Assistance Provider, MDHHS matched RWHAP and HIV and HCV surveillance data, calculated HCV viral clearance cascades for coinfected populations, and worked with three RWHAP clinics to generate clinic-based lists of coinfected clients and conduct outreach and linkage to HCV treatment.
  • Best Practices Compilation
    The HIV clinic at Washington University integrated comprehensive hepatitis C virus (HCV) screening and treatment into its care model. Chronic HCV is a “silent” infection as it damages the liver over time, often without symptoms. Early treatment of HCV is particularly important among people with HIV, as HIV accelerates HCV’s progression. Of the 1,711 clients served at the clinic each year, 174 had a detectable HCV viral load. These clients received integrated clinical and support services to reduce barriers to ongoing HCV care engagement.
  • Best Practices Compilation
    The University of California San Francisco, San Francisco General Hospital HIV Clinic developed a care model to enhance access to hepatitis C virus (HCV) treatment among people with HIV by co-locating care and creating a multidisciplinary team. Developed as part of the RWHAP Part F SPNS Hepatitis C Treatment Expansion Initiative, this model of care led to a considerable decrease in the number of people with HIV who were coinfected with HCV among the patients served by San Francisco General Hospital during the 2010 and 2011 demonstration years.


Training Modules

  • SPNS HIV/HCV Data-to-Care Initiative
    Mini-modules on the steps required to use available public health datasets to create and act upon HIV and hepatitis C viral clearance cascades.
  • University of Washington

    Hepatitis C infection resources for medical providers with a listing of HCV medication, online training modules, slide lectures, tools and calculators, and a bibliography.


Conference Presentations

Pennsylvania State University
Sarah Brothers, Ditas Villanueva
2022 National Ryan White Conference on HIV Care & Treatment
University of Washington
2022 Ryan White HIV/AIDS Program Clinical Conference
Northwestern University
Marion G. Peters, MD
2020 Ryan White HIV/AIDS Program Clinical Conference
University of Massachusetts, Lowell
Serena Rajabiun, Brandon Williams
2020 National Ryan White Conference on HIV Care & Treatment
Saint Francis Hospital and Medical Center
2020 National Ryan White Conference on HIV Care & Treatment

Technical Assistance

  • The central hub of the AETC Program, the clinical training arm of the RWHAP, through HIV curricula, technical support to regional AETCs on practice transformation and best practices, and housing of all AETC-developed tools for HIV clinical staff. Project period: 2019-2024.
  • Clinician consultation on HCV management, HIV management, perinatal HIV/AIDS, pre-exposure prophylaxis (PrEP), post-exposure prophylaxis, substance use. Project period: 2016-2025.

  • SPNS initiative aimed to link individuals co-infected with HIV and HCV to care by leveraging public health surveillance and clinical data systems. Project period: 2020-2022.
  • The NHC provides ongoing, up-to-date information needed to meet the core competency knowledge for HIV prevention, screening, diagnosis, and ongoing treatment and care to healthcare providers in the United States. Project period: 2020-2022.
  • Initiative documenting best practice strategies and interventions that have been shown to improve HIV outcomes in a "real world" setting and can be replicated by other programs. Project period: 2021-2024.

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