Antiretroviral Treatment

Collaborative Care Management (CoCM) integrates mental health and primary care, with a care team of a primary care provider, behavioral health care manager, and psychiatric consultant. Together they provide comprehensive and coordinated care to people with HIV who have co-occurring depression or other psychiatric disorders. Four sites implemented CoCM as part of E2i, an initiative funded by the RWHAP Part F SPNS program from 2017–2021. CoCM led to statistically significant increases in antiretroviral therapy (ART) prescription and viral suppression.

Ten organizations across the U.S. integrated Community Health Workers (CHWs) into their multidisciplinary care teams. Enrolled clients had statistically significant improvements in viral suppression, antiretroviral therapy prescription, and appointment attendance after six months in the program.

Healthy Divas focuses on empowering transgender women with HIV to achieve their personal health goals. Three sites implemented the intervention as part of the E2i initiative funded through the RWHAP Part F SPNS program from 2017 through 2021. Both engagement in HIV care and having an antiretroviral therapy prescription improved significantly for clients 12 months after enrollment in Healthy Divas.

The HIV Clinical Pharmacist Services intervention shortens the time between referral to and engagement in care by allowing newly referred clients to see pharmacists in addition to other clinical providers for their initial appointment. This intervention is supported by findings from a retrospective cohort study that took place from 2013 to 2017 at a RWHAP-funded clinic. In addition to significantly decreasing the time between referral and initial visit, clients who saw a pharmacist also experienced shortened time to antiretroviral therapy initiation and viral suppression compared to those who only saw non-pharmacist providers.

JumpstART launched in 2016 as part of New York State’s Ending the Epidemic initiative, changing the service delivery model of eight sexual health clinics to include an initial prescription of ART after an HIV diagnosis and prior to linkage to the community provider. Between November 2016 and September 2018, 60% of JumpstART clients received ART on the same day as diagnosis. JumpstART clients were also more likely to reach viral suppression within three months compared to non-JumpstART clients.

Link-Up Rx is a data to care (D2C) program that aims to increase retention in care and viral suppression among people with HIV by using prescription refill information to decrease the length of time between refills and reduce antiretroviral therapy (ART) interruption.

The RWHAP Part F SPNS program funded the Building a Medical Home for Multiply Diagnosed HIV-Positive Homeless Populations initiative from 2012–2017, to provide coordinated housing supports and HIV, behavioral and mental health care to people experiencing homelessness. Nine funded demonstration sites created partnerships with housing providers, integrated behavioral health and HIV care, and provided intensive patient navigator services. A multi-demonstration site evaluation found that, compared to baseline, participants were more likely to be virally suppressed after 12 months in the intervention.

Project CONNECT uses linkage coordinators to effectively engage people in HIV medical care. It focuses on people with newly diagnosed HIV or people with HIV who are transferring their care or have been out of care. AIDS Taskforce of Greater Cleveland implemented Project CONNECT as part of E2i, an initiative funded by the RWHAP Part F SPNS program from 2017–2021. Project CONNECT was successful in increasing the number of clients retained in HIV care and who reached viral suppression.

HIV clinical training resources for HRSA's AIDS Education and Training Centers Program.

CPAPA is no longer being updated by NASTAD and has been replaced by Pharmaceutical Company Patient Assistance Programs and Cost-Sharing Assistance Programs.

Healthcare providers can receive no-cost expert clinical consultation in HIV prevention & care, HCV treatment, and substance use management.

Online clinician training platform with evidence-based core competency training on HIV prevention, screening, diagnosis, care, and key populations.

U.S. HIV-related treatment guidelines, drug database, and glossary.

Federal guidelines for treatment, prevention and care of HIV disease, opportunistic infections, and common co-infections. 

Information on HRSA's Office of Pharmacy Affairs, which administers the 340b program, which provides drug discounts to certain federal grantees,

Guide for EHE jurisdictions on what they can do to enhance implementation of long-acting injectable antiretroviral therapy.

Fact sheet on the different coverage and cost-sharing considerations for LAI ART across public and private payers.

What HIV care providers can do to create a rapid ART program to get HIV clients on treatment the same day as a diagnosis.

Pre-application webinars for Notice of Funding Opportunity (NOFO) announcements from HRSA's HIV/AIDS Bureau for the Ryan White HIV/AIDS Program (RWHAP).

Review of the data to care project and lessons learned on HCV micro-elimination activities from the Arizona Department of Health Services.

Role of health centers in increasing PrEP access and use among women.

Learn how to improve messaging about HIV prevention and care to improve acceptance of services among all Black women.

In 2021, the U.S. public was introduced to a bi-monthly injectable form of PrEP, which stands for Pre-Exposure Prophylaxis.

In this Microlearning segment, learn what types of injectable long lasting HIV prevention and treatment medications are available, and their similarities and differences.

Review of concept of status neutral (access to HIV services regardless of HIV status).

Recordings of the TAP-in webinars on topics critical to the Ending the HIV Epidemic Initiative.