CIE Interventions

These interventions have been proven effective in engaging people with HIV who are not receiving HIV care or who are at risk of falling out of care. Each summary outlines the intervention components, outcomes, cost information (where available), and known challenges and solutions. Supplementary resources, such as publications and job aids, are also included.

Compendium of Evidence-informed Approaches to Improving Health Outcomes for People Living with HIV


TAVIE Red is a mobile application that utilizes gamification to increase health and psychological self-management and assists case managers with connecting with clients.

MORE Intervention

Tailored service delivery model including increasing access to supportive services and the provision of HIV care services in community settings.

Project ACCEPT

A group-based intervention for cisgender youth, 16- to 24-years old, to improve engagement in HIV care


A clinic-based mobile app to promote linkage to and engagement in HIV care by connecting clients to a virtual local community

Tailored Motivational Interviewing

Motivational Interviewing reimagined for youth with new HIV diagnoses to ultimately improve retention in HIV care

Clinic-Based Surveillance-Informed

Combines clinic and health department surveillance data to identify and re-engage people with HIV who are out of care

Project STYLE

An innovative model that links youth to the care step of the HIV care continuum

Linkage to Care Specialist Project

A client-centered, resiliency-based model to link newly diagnosed individuals to HIV care

Emergency Department and Hospital-Based Data Exchange

A  real-time data to care program to identify and re-engage people with HIV in care

Housing Interventions to Promote Retention in Care

Rental assistance, housing placement assistance, or supportive permanent housing for low-income persons with HIV

Project START

A client-focused, personalized, Incremental Risk Reduction approach to improve linkage and retention in care among people leaving correctional facilities

Link-Up Rx

A data to care (D2C) program that aims to increase retention in care and viral suppression among people with HIV by using prescription refill information to decrease the length of time between refills and reduce antiretroviral therapy (ART) interruption.